Proximity and orientation underlie signaling by the non-receptor tyrosine kinase ZAP70
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چکیده
منابع مشابه
Proximity and orientation underlie signaling by the non-receptor tyrosine kinase ZAP70.
Signaling by the antigen receptor of T lymphocytes initiates different developmental transitions, each of which require the tyrosine kinase ZAP70. Previous studies with agonist and antagonist peptides have indicated that ZAP70 might respond differently to different structures of the TCR-CD3 complex induced by bound peptides. The roles of membrane proximity and orientation in activation of ZAP70...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 1997
ISSN: 1460-2075
DOI: 10.1093/emboj/16.18.5618